1196541-47-5
Chemical Structure
GDC-0575
Synonym(s): ARRY-575; RG7741
- CAS No.: 1196541-47-5
- Formula:C16H20BrN5O
- Molecular Weight:378.27
IUPAC Name: (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide
InChIKey: BAZRWWGASYWYGB-SNVBAGLBSA-N
SMILES: O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32
Biological Activity: GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GDC-0575 | 99.68% | GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
GDC-0575-d4 | GDC-0575-d4 (ARRY-575-d4) is the deuterium labeled GDC-0575 (HY-112167). GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.98
HY-112167BGDC0575 hydrochloride -
Similarity Score 0.97
HY-112167AGDC-0575 dihydrochloride -
Similarity Score 0.50
HY-183451Y-30141 -
Similarity Score 0.44
HY-117413SR-17398 -
Similarity Score 0.44
HY-132969SBP-3264 -
Similarity Score 0.44
HY-114043NCGC00092410 -
Similarity Score 0.43
HY-101941RBTK IN-1 (Standard) -
Similarity Score 0.42
HY-108342PF-00956980 -
Similarity Score 0.42
HY-161661Anticancer agent 223 -
Explore the MedChemAI to find more analogs