1196541-47-5

GDC-0575 Chemical Structure
1196541-47-5

Chemical Structure

GDC-0575

Synonym(s): ARRY-575; RG7741

  • CAS No.: 1196541-47-5
  • Formula:C16H20BrN5O
  • Molecular Weight:378.27

IUPAC Name: (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide

InChIKey: BAZRWWGASYWYGB-SNVBAGLBSA-N

SMILES: O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32

Biological Activity: GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.

Cat. No. Product Name Purity Description Pricing
HY-112167
GDC-0575 99.68% GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.
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HY-112167S
GDC-0575-d4 GDC-0575-d4 (ARRY-575-d4) is the deuterium labeled GDC-0575 (HY-112167). GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.
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