GDC-0575-d4
GDC-0575-d4 (ARRY-575-d4) is the deuterium labeled GDC-0575 (HY-112167). GDC-0575 (ARRY-575, RG7741) is a highly-selective oral small-molecule Chk1 inhibitor with an IC50 of 1.2 nM.
For research use only. We do not sell to patients.
- Formula: C16H16D4BrN5O
- Molecular Weight:382.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1196541-47-5
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Molecular Weight 382.29
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Formula C16H16D4BrN5O
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SMILES
O=C(C1C([2H])([2H])C1([2H])[2H])NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32
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Synonyms
ARRY-575-d4; RG7741-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GDC-0575-d4 Related Classifications
HY-112167S Related Classifications
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