127-40-2
127-40-2
Chemical Structure
Lutein
Synonym(s): Xanthophyll
- CAS No.: 127-40-2
- Formula:C40H56O2
- Molecular Weight:568.87
IUPAC Name: (1R,4R)-4-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-((R)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl)-3,5,5-trimethylcyclohex-2-en-1-ol
InChIKey: KBPHJBAIARWVSC-RGZFRNHPSA-N
SMILES: CC(/C=C/[C@@H](C(C)=C[C@H](O)C1)C1(C)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C(C(C)(C[C@H](O)C2)C)=C2C
Biological Activity: Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health[1]. Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti-apoptosis, through effects on reactive oxygen species (ROS)[2][3]. Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active[4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lutein | 90.0% | Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health. Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti-apoptosis, through effects on reactive oxygen species (ROS). Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active. | ||||||||||||||||||||
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β-Cryptoxanthin | β-Cryptoxanthin ((3R)-β-Cryptoxanthin) is an orally active carotenoid found in fruits and vegetables such as angerines, red peppers, and pumpkin. β-Cryptoxanthin inhibits prevents osteoclast formation and inhibits bone resorption. β-Cryptoxanthin maintains retinol status in vivo. β-cryptoxanthin shows anti-inflammation and anticancer activity. β-Cryptoxanthin can be used for the researches of osteoporosis and bladder carcer. | |||||||||||||||||||||
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α-Carotene | 95.0% | α-Carotene, a precursor of vitamin A, is used as an anti-metastatic agent or as an adjuvant for anti-cancer agents. α-Carotene is isolated from yellow-orange and dark-green vegetables. | ||||||||||||||||||||
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Zeaxanthin | 95.0% | Zeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye. Zeaxanthin shows antioxidant effects. | ||||||||||||||||||||
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Tunaxanthin | Tunaxanthin is a xanthophyll, exists in fruits of various tomato strains and their hybrid. Tunaxanthin is also a carotenoid present in fish. | |||||||||||||||||||||
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meso-Zeaxanthin | 93.09% | meso-Zeaxanthin ((3R,3′S)-Zeaxanthin) is an orally active xanthophyll carotenoid. meso-Zeaxanthin inhibits CYP1A1, CYP1A2, CYP2B1/2, COX-2, TNF-α and iNOS, and enhances the activities of Uridine diphosphate glucuronosyltransferase and Glutathione-S-transferase. meso-Zeaxanthin quenches oxygen free radicals. meso-Zeaxanthin filters short-wavelength blue light, alleviates oxidative damage and visual abnormalities. meso-Zeaxanthin reduces tumor incidence, prolongs tumor latency and survival rate of tumor-bearing mice, and inhibits paw edema. meso-Zeaxanthin can be used in research related to sarcoma and age-related macular degeneration. | ||||||||||||||||||||
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α-Cryptoxanthin | α-Cryptoxanthin is a natural carotenoid with anticancer effects. α-Cryptoxanthin inhibits multidrug resistance 1 (MDR1) mediated efflux pump. | |||||||||||||||||||||
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Anhydrolutein I | Anhydrolutein I is a dehydration product of Lutein (HY-N6947). Anhydrolutein I can be isolated from the extract of steam-cooked sorrel. | |||||||||||||||||||||
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Anhydrolutein II | Anhydrolutein II, a carotenoid, is a dehydration product of Lutein (HY-N6947). | |||||||||||||||||||||
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3′-Oxolutein | 3′-Oxolutein, a metabolite of dietary lutein, is an anti-inflammatory agent and antioxidant, 3′-Oxolutein mitigates the effects of glutamate-induced ROS production and proinflammatory cytokine secretions in SH-SY5Y cells. 3'-Oxolutein reduces glutamate-induced iron content and increases thiol levels. 3′-Oxolutein can be used for the study of inflammation. | |||||||||||||||||||||
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β-Citraurin | β-Citraurin is a carotenoid. Jasmonates induce β-Citraurin biosynthesis in citrus by activating a CsMPK6-CsMYC2 cascade, thereby affecting fruit coloration. | |||||||||||||||||||||
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References
- [1]. Buscemi S, et al. The Effect of Lutein on Eye and Extra-Eye Health.Nutrients. 2018 Sep 18;10(9). pii: E1321. [Content Brief]
- [2]. Kim SR, et al. Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Exp Eye Res. 2006 May;82(5):828-39. [Content Brief]
- [3]. Tan D, et al. Lutein protects against severe traumatic brain injury through anti‑inflammation and antioxidative effects via ICAM‑1/Nrf‑2. Mol Med Rep. 2017 Oct;16(4):4235-4240. [Content Brief]
- [4]. Zeni ALB, et al. Lutein prevents corticosterone-induced depressive-like behavior in mice with the involvement of antioxidant and neuroprotective activities. Pharmacol Biochem Behav. 2019 Apr;179:63-72. [Content Brief]
