129-67-9
Chemical Structure
Demethylcantharidate disodium
- CAS No.: 129-67-9
- Formula:C8H8Na2O5
- Molecular Weight:230.13
IUPAC Name: sodium 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate
InChIKey: XRHVZWWRFMCBAZ-UHFFFAOYSA-L
SMILES: O=C(C1C(C2OC1CC2)C(O[Na])=O)O[Na]
Biological Activity: Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Demethylcantharidate disodium | 98.0% | Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer. | ||||||||||||||||||||
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Endothall | 99.88% | Endothall (Endothal) is a protein phosphatase 2A (PP2A) inhibitor with IC50s of 90 nM and 5 µM for PP2A and PP1, respectively. Endothall can be used as an herbicide. Endothall also is useful in cancer chemotherapy. | ||||||||||||||||||||
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Cantharidic acid | Cantharidic acid is a Cantharidin (HY-N0209) analog, anticancer agent, and selective Ser/thr phosphatase 1 and 2A inhibitor. Cantharidic acid induces ROS, Mitochondrial dysfunction, LDH release, cell cycle arrest, and Apoptosis. Cantharidic acid decreases Nrf2, HO-1, and GPX4, and reduces PCNA, MMP2, and MMP9. Cantharidic acid can be used in research on colorectal cancer, hepatocellular carcinoma, oral squamous cell carcinoma, and adenocarcinoma. | |||||||||||||||||||||
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Humic acid sodium,50-60% (as humic acid) | Humic acid (sodium) is a Miscellaneous product that can be isolated from the herbs of Oryza sativa. | |||||||||||||||||||||
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1,3-Bis(methoxycarbonyl)cyclopentane | 99.65% | 1,3-Bis(methoxycarbonyl)cyclopentane (Norcamphoric acid, dimethyl ester) is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
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cis-2-(Methoxycarbonyl)cyclopentanecarboxylic acid | 98.0% | cis-2-(Methoxycarbonyl)cyclopentanecarboxylic acid is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
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Sodium Demethylcantharidate | Sodium Demethylcantharidate is an endogenous metabolite. | |||||||||||||||||||||
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4-(Methoxycarbonyl)cyclohexane-1-carboxylic acid | ≥98.0% | 4-(Methoxycarbonyl)cyclohexane-1-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Disodium succinate (Standard) | 99.99% | Disodium succinate (Standard) is the analytical standard of Disodium succinate. This product is intended for research and analytical applications. Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields. | ||||||||||||||||||||
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Dimethyl trans-1,4-cyclohexanedicarboxylate | Dimethyl trans-1,4-cyclohexanedicarboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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2,3-Norbornanedicarboxylic acid | 2,3-Norbornanedicarboxylic acid (Bicyclo[2.2.1]heptane-2,3-dicarboxylic Acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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