129-77-1
129-77-1
Chemical Structure
Piperidolate hydrochloride
- CAS No.: 129-77-1
- Formula:C21H26ClNO2
- Molecular Weight:359.89
IUPAC Name: 1-ethylpiperidin-3-yl 2,2-diphenylacetate hydrochloride
InChIKey: RBGWCEWDAHDPEH-UHFFFAOYSA-N
SMILES: O=C(OC1CN(CC)CCC1)C(C2=CC=CC=C2)C3=CC=CC=C3.[H]Cl
Biological Activity: Piperidolate hydrochloride is a cholinergic antagonist. Piperidolate hydrochloride prevents ventricular fibrillation during hypothermic cardiac manipulations to support cardiac procedures post-preoperative defibrillation. Piperidolate hydrochloride causes dose-dependent cardiac depression. Piperidolate hydrochloride can be used for the research of ventricular fibrillation[1][2].
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Piperidolate hydrochloride | 99.66% | Piperidolate hydrochloride is a cholinergic antagonist. Piperidolate hydrochloride prevents ventricular fibrillation during hypothermic cardiac manipulations to support cardiac procedures post-preoperative defibrillation. Piperidolate hydrochloride causes dose-dependent cardiac depression. Piperidolate hydrochloride can be used for the research of ventricular fibrillation. | ||||||||||||||||||||
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References
- [1]. HARA M, et al. Antifibrillatory action of piperidolate hydrochloride (dactil) in hypothermia. AMA Arch Surg. 1957 Nov;75(5):780-4. [Content Brief]
- [2]. Ozawa H, et al. Effect of Piperidolate, which Has Antispasmodic Effects, on Removed Smooth Muscle, Especially Uterine Smooth Muscle Under Sex Hormone Influence (1). Japanese Journal of Pharmacology. 1974;70(5):659-671.
