13057-72-2
Chemical Structure
7-Hydroxyisoflavone
- No. CAS: 13057-72-2
- Formula:C15H10O3
- Molecular Weight:238.24
IUPAC Name: 7-hydroxy-3-phenyl-4H-chromen-4-one
InChIKey: WMKOZARWBMFKAS-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=CC=C2)=COC3=C1C=CC(O)=C3
Biological Activity: 7-Hydroxyisoflavone is an enterovirus replication inhibitor. 7-Hydroxyisoflavone inhibits enterovirus 71 viral RNA synthesis, viral protein synthesis, and early replication steps. 7-Hydroxyisoflavone also inhibits coxsackievirus replication. 7-Hydroxyisoflavone enhances AMPK activity and prevents serum-induced reduction of AMPK phosphorylation. 7-Hydroxyisoflavone can be used in research related to enterovirus infection[1][2].
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7-Hydroxyisoflavone | 99.75% | 7-Hydroxyisoflavone is an enterovirus replication inhibitor. 7-Hydroxyisoflavone inhibits enterovirus 71 viral RNA synthesis, viral protein synthesis, and early replication steps. 7-Hydroxyisoflavone also inhibits coxsackievirus replication. 7-Hydroxyisoflavone enhances AMPK activity and prevents serum-induced reduction of AMPK phosphorylation. 7-Hydroxyisoflavone can be used in research related to enterovirus infection. | ||||||||||||||||||||
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Similarity Score 0.87
HY-N66317-Methoxyisoflavone -
Similarity Score 0.85
HY-N0019RDaidzein (Standard) -
Similarity Score 0.84
HY-W006405Isoflavone -
Similarity Score 0.83
HY-N0094Ipriflavone -
Similarity Score 0.82
HY-W5085527-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one -
Similarity Score 0.81
HY-N0183Formononetin -
Similarity Score 0.80
HY-1249537,3',4'-Trihydroxyisoflavone -
Similarity Score 0.79
HY-N7501RIsoformononetin (Standard) -
Similarity Score 0.78
HY-W2071957-Hydroxy-4-phenylcoumarin -
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References
- [1]. Wang HQ, et al. The antiviral effect of 7-hydroxyisoflavone against Enterovirus 71 in vitro. Journal of Asian natural products research. 2013 Apr 1;15(4):382-9.
- [2]. Jung H, et al. Isoflavones as modulators of adenosine monophosphate-activated protein kinase. Applied Biological Chemistry. 2016 Apr;59(2):217-25.
