134-04-3
Chemical Structure
Pelargonidin chloride
- CAS No.: 134-04-3
- Formula:C15H11ClO5
- Molecular Weight:306.70
IUPAC Name: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromenylium chloride
InChIKey: YPVZJXMTXCOTJN-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=C(O)C=C3C(C=C(O)C=C3O)=[O+]2)C=C1.[Cl-]
Biological Activity: Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment[1][2][3].
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Pelargonidin chloride | 98.52% | Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment. | ||||||||||||||||||||
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- [1]. S A van Acke, et al. Flavonoids as Scavengers of Nitric Oxide Radical.Biochem Biophys Res Commun. 1995 Sep 25;214(3):755-9. [Content Brief]
- [2]. Soleimani Asl S, et al. Pelargonidin exhibits restoring effects against amyloid β-induced deficits in the hippocampus of male rats. Med J Islam Repub Iran. 2019 Dec 12;33:135. [Content Brief]
- [3]. Li S, et al. Pelargonidin reduces the TPA induced transformation of mouse epidermal cells -potential involvement of Nrf2 promoter demethylation. Chem Biol Interact. 2019 Aug 25;309:108701. [Content Brief]
Keywords
