1350544-93-2
1350544-93-2
Chemical Structure
Ruserontinib
Synonym(s): SKLB1028
- CAS No.: 1350544-93-2
- Formula:C24H29N9
- Molecular Weight:443.55
IUPAC Name: 9-isopropyl-N2-(4-(4-methylpiperazin-1-yl)phenyl)-N8-(pyridin-3-yl)-9H-purine-2,8-diamine
InChIKey: WSOHOUHPUOAXIN-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C4N=C(N(C4=N3)C(C)C)NC5=CC=CN=C5
Biological Activity: Ruserontinib (SKLB1028) is an orally active multikinase inhibitor of EGFR, FLT3 and Abl, with an IC50 value of 55 nM for human FLT3, and has antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ruserontinib | 99.32% | Ruserontinib (SKLB1028) is an orally active multikinase inhibitor of EGFR, FLT3 and Abl, with an IC50 value of 55 nM for human FLT3, and has antitumor activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-120412SKLB188 -
Similarity Score 0.65
HY-150905EGFR ligand-2 -
Similarity Score 0.62
HY-130616EGFR-IN-11 -
Similarity Score 0.62
HY-173118EGFR-IN-152 -
Similarity Score 0.57
HY-151279ALK5-IN-30 -
Similarity Score 0.57
HY-162808GTSE1-IN-1 -
Similarity Score 0.57
HY-143337EGFR-IN-47 -
Similarity Score 0.56
HY-175013CDK6/9-IN-2 -
Similarity Score 0.56
HY-138966SM1-71-R -
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