1354448-60-4
1354448-60-4
Chemical Structure
KH-CB20
- CAS No.: 1354448-60-4
- Formula:C15H13Cl2N3O2
- Molecular Weight:338.19
IUPAC Name: ethyl (E)-3-(2-amino-1-cyanovinyl)-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
InChIKey: CXJCGSPAPOTTSF-VURMDHGXSA-N
SMILES: CCOC(C1=C(C2=C(C(Cl)=C(C=C2)Cl)N1C)/C(C#N)=C\N)=O
Biological Activity: KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1 and the closely related isoform CLK4, with an IC50 of 16.5 nM for CLK1. KH-CB20 can also inhibit DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KH-CB20 | 99.80% | KH-CB20, an E/Z mixture, is a potent and selective inhibitor of CLK1 and the closely related isoform CLK4, with an IC50 of 16.5 nM for CLK1. KH-CB20 can also inhibit DYRK1A (IC50=57.8 nM) and CLK3 (IC50=488 nM). | ||||||||||||||||||||
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References
Keywords
