1400699-64-0
1400699-64-0
Chemical Structure
Elismetrep
Synonym(s): MT-8554
- CAS No.: 1400699-64-0
- Formula:C27H21F3N2O5S
- Molecular Weight:542.53
IUPAC Name: 4-(N-(4-cyclopropylisoquinolin-3-yl)-N-(4-(trifluoromethoxy)benzyl)sulfamoyl)benzoic acid
InChIKey: CWEFDWIKLABKBX-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(S(=O)(N(CC2=CC=C(C=C2)OC(F)(F)F)C3=C(C4CC4)C5=CC=CC=C5C=N3)=O)C=C1)O
Biological Activity: Elismetrep (MT-8554) is a TRPM8 channel antagonist and neuroprotective agent. Elismetrep is used for research on pain, menopause-related vasomotor symptoms, and diabetic peripheral neuropathy[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Elismetrep | 99.59% | Elismetrep (MT-8554) is a TRPM8 channel antagonist and neuroprotective agent. Elismetrep is used for research on pain, menopause-related vasomotor symptoms, and diabetic peripheral neuropathy. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Conklin M, et al. Neurokinin receptor antagonists as potential non-hormonal treatments for vasomotor symptoms of menopause. Therapeutic advances in reproductive health. 2023;17:26334941231177611. [Content Brief]
- [2]. Weyer AD, et al. Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine. Pharmaceuticals (Basel, Switzerland). 2017 Mar 30;10(2):37. [Content Brief]
- [3]. Genazzani AR, et al. Oral investigational drugs currently in phase I or phase II for the amelioration of menopausal symptoms. Expert opinion on investigational drugs. 2019 Mar;28(3):235-247. [Content Brief]
Keywords
