2. Metabolic Enzyme/Protease
  3. MMP
  4. WAY-170523

WAY-170523 is a potent and selective MMP-13 (matrix metalloproteinase-13) inhibitor, with an IC50 of 17 nM. WAY-170523 can directly attenuate ERK1/2 phosphorylation. WAY-170523 inhibits the invasion of PC-3 cells, can be used for prostate cancer research.

For research use only. We do not sell to patients.

WAY-170523 Chemical Structure

WAY-170523 Chemical Structure

CAS No. : 307002-73-9

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WAY-170523 Related Antibodies

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

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Description

WAY-170523 is a potent and selective MMP-13 (matrix metalloproteinase-13) inhibitor, with an IC50 of 17 nM. WAY-170523 can directly attenuate ERK1/2 phosphorylation. WAY-170523 inhibits the invasion of PC-3 cells, can be used for prostate cancer research[1][2].

IC50 & Target

MMP13

17 nM (IC50)

MMP-9

945 nM (IC50)

MMP-1

10 μM (IC50)

In Vitro

WAY-170523 has an IC50 of 17 nM for MMP-13 and shows > 5800-, 56-, and > 500-fold selectivity against MMP-I, MMP-9, and TACE, respectively.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

WAY-170523 Related Antibodies
Molecular Weight

613.68

Formula

C33H31N3O7S
CAS No.
SMILES

O=C(C1=CC2=C(C=CC=C2)O1)NCCOC3=CC=C(S(=O)(N(CC4=CC=CC=C4)C5=C(C)C=C(C)C=C5C(NO)=O)=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WAY-170523 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WAY-170523307002-73-9WAY170523WAY 170523MMPMatrix metalloproteinasesPC-3 cellsProstate cancerMatrix metalloproteinaseHeart failure (HF)Inhibitorinhibitorinhibit

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