Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine
- Pharmaceuticals (Basel). 2017 Mar 30;10(2):37. doi: 10.3390/ph10020037.
Affiliations
- 1. Pacific University School of Physical Therapy, Hillsboro, OR 97123, USA. [email protected].
- 2. One Amgen Center Dr, Thousand Oaks, CA 91320, USA. [email protected].
PMID: 28358322
DOI: 10.3390/ph10020037
Abstract
A review. Development of pharmaceutical antagonists of transient receptor potential melastatin 8 (TRPM8) have been pursued for the treatment of Chronic Pain and Migraine. This review focuses on the current state of this progress.
Keywords
cold analgesia; cold hyperalgesia; mechanical hyperalgesia; menthol; migraine; pain; transient receptor potential melastatin 8 (TRPM*).
Products
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Cat. No.Product NameDescriptionTargetResearch Area
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target: TRP Channel