141-94-6
Chemical Structure
Hexetidine
Synonym(s): NSC-17764
- CAS No.: 141-94-6
- Formula:C21H45N3
- Molecular Weight:339.60
IUPAC Name: 1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine
InChIKey: DTOUUUZOYKYHEP-UHFFFAOYSA-N
SMILES: NC1(C)CN(CC(CC)CCCC)CN(CC(CC)CCCC)C1
Biological Activity: Hexetidine (NSC-17764) is an orally active antibacterial and antifungal agent with broad antibacterial and antifungal activity. Hexetidine combined with IPBC potentiates strong fungal growth inhibition properties. Hexetidine at concentrations greater than 0.1% can cause oral ulceration. Additionally, Hexetidine improves its plaque inhibiting activities combined with zinc and has been confirmed the effectiveness on purulent wound along with ultrasound. Hexetidine is a promising candidate for research in fungus-related diseases and soft tissue purulent-inflammatory[1][2][3][4][5]
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Hexetidine | 98.0% | Hexetidine (NSC-17764) is an orally active antibacterial and antifungal agent with broad antibacterial and antifungal activity. Hexetidine combined with IPBC potentiates strong fungal growth inhibition properties. Hexetidine at concentrations greater than 0.1% can cause oral ulceration. Additionally, Hexetidine improves its plaque inhibiting activities combined with zinc and has been confirmed the effectiveness on purulent wound along with ultrasound. Hexetidine is a promising candidate for research in fungus-related diseases and soft tissue purulent-inflammatory | ||||||||||||||||||||
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Hexetidine (Standard) | ≥98% | Hexetidine (Standard) is the analytical standard of Hexetidine. This product is intended for research and analytical applications. Hexetidine is an orally active antiseptic with broad antibacterial and antifungal activity. Hexetidine give important potential for treatment of oral infections. | ||||||||||||||||||||
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- [1]. Vallières C, et al. Potentiated inhibition of Trichoderma virens and other environmental fungi by new biocide combinations[J]. Appl Microbiol Biotechnol. 2021 Apr;105(7):2867-2875. [Content Brief]
- [2]. Dr. Sandhya Gnanasambandam, et al. Role of supra-gingival plaque in the pathophysiology of periodontitis. World Journal of Pharmaceutical Research. 2024 April 12; 13(8): 902-915.
- [3]. Afennich F, et al. The effect of hexetidine mouthwash on the prevention of plaque and gingival inflammation: a systematic review.Int J Dent Hyg. 2011 Aug;9(3):182-90. [Content Brief]
- [4]. Ivan S. Dragovoz, et al. Comparative Evaluation of Isolated and Complex Use of Hexetidine and Photoditazine in Combination with Ultrasound Therapy in the Treatment of Purulent Wounds under Experimental Conditions[J]. International Journal of Biomedicine. 2022 March 20; 12(1):138-141
- [5]. Gorman SP, et al. The concomitant development of poly(vinyl chloride)-related biofilm and antimicrobial resistance in relation to ventilator-associated pneumonia[J]. Biomaterials. 2001 Oct;22(20):2741-7. [Content Brief]
Keywords
