4-Dodecyl-2,6-dimethylmorpholine
4-Dodecyl-2,6-dimethylmorpholine is a morpholine fungicide and plant-growth regulator. 4-Dodecyl-2,6-dimethylmorpholine targets phytopathogenic fungi including Oomycetes, Ascomycetes and Basidiomycetes. 4-Dodecyl-2,6-dimethylmorpholine acts synergistically with acylalanine fungicides to enhance antifungal efficacy and regulate plant growth. 4-Dodecyl-2,6-dimethylmorpholine can be applied to the study of plant fungal diseases and phytopathogenic fungal infections.
For research use only. We do not sell to patients.
- CAS No.: 1704-28-5
- Formula: C18H37NO
- Molecular Weight:283.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
4-Dodecyl-2,6-dimethylmorpholine (Aldimorph) (0.4-40 mg/l; 5 days), which is the main component of Aldimorph, inhibits radial growth of Phytophthora cinnamomi in vitro with 64% inhibition at 40 mg/L and 1% inhibition at both 4 mg/L and 0.4 mg/L after 5 days of incubation[1].
4-Dodecyl-2,6-dimethylmorpholine inhibits the vegetative (radial) growth of multiple Phytophthora species, with corresponding ED50 values of 32.7 mg/l (P. cactorum), 36.2 mg/l (P. cambivora), 32.5 mg/l (P. citricola), and 517.6 mg/l (P. parasitica var. nicotianae)[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
4-Dodecyl-2,6-dimethylmorpholine (1040.0 mg/L; immersion; single treatment) exhibits activity against sunflower downy mildew with an ED50 of 1040.0 mg/L when applied as a post-infection immersion treatment[2].
4-Dodecyl-2,6-dimethylmorpholine (40–50 mg/L; immersion; dark conditions) reduces sunflower hypocotyl length, and its growth-inhibitory effect is antagonized by 10 mg/L phenylamide fungicides[1].
4-Dodecyl-2,6-dimethylmorpholine (0.1 mg/L; foliar spray; 12 days/four-leaf stage) induces a 111% increase in tomato dry weight and synergistically promotes plant growth with phenylamide fungicides[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Helianthus annus[1]
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Dosage:40 mg/L (alone); 50 mg/L (combined with 10 mg/L cyprofuram); 50 mg/L (combined with 10 mg/L LAB 149202F); 50 mg/L (combined with 10 mg/L metalaxyl); 50 mg/L (combined with 10 mg/L Ofurace); 50 mg/L (combined with 10 mg/L RE 26745)
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Administration:immersion treatment
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Result:Reduced sunflower hypocotyl length to 3.7 cm in dark conditions (control = 8.3 cm in light, 3.7 cm in dark) at 40 mg/L.
Increased sunflower hypocotyl length to 7.4 cm, 8.4 cm, 7.5 cm, 7.8 cm and 6.7 cm in dark conditions when combined with 10 mg/L cyprofuram, LAB 149202F, Metalaxyl (HY-B0843), Ofurace (HY-122451) and RE 26745 respectively.
Showed no correlation between phenylamide-induced growth stimulation and antagonism of aldimorph's growth-inhibiting effect.
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Animal Model:Helianthus annus cv. GK-70[1]
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Dosage:1040 mg/L (immersion); 50 mg/L (foliar spray); 5.4 mg/L (combined with RE 26745, 3:1 ratio); 50 mg/L (combined with cyprofuram, 7:5 ratio)
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Administration:immersion; 18 hours; foliar spray (curative application)
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Result:Showed no measurable efficacy against sunflower downy mildew at 1040 mg/L.
Inhibited Plasmopara halstedii sporulation by 0% at 50 mg/L.
Achieved a 5.57 Comparative Toxicity Index (CoTI), indicating significant synergistic efficacy.
Inhibited sporulation by 82% with a 37% synergistic effect relative to individual components.
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Animal Model:Solanum lycopersicum cv. Harz feuer[1]
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Dosage:0.1 mg/L (alone); 0.01:0.05 mg/L (combined with Ofurace); 0.01:0.05 mg/L (combined with cyprofuram); 0.01:0.05 mg/L (combined with LAB 149 202 F); 0.01:0.03 mg/L (combined with RE 26745)
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Administration:foliar spray to run-off; 12 days
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Result:Increased tomato plant dry weight by 11% relative to the untreated control with no significant difference at 0.1 mg/L.
Increased tomato plant dry weight by 22%, 21%, 20% and 22% when combined with Ofurace, cyprofuram (0.01:0.05 mg/L), LAB 149 202 F (0.01:0.05 mg/L) and RE 26745 (0.01:0.03 mg/L), respectively.
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Animal Model:Solanum lycopersicum cv. Harzfeuer (four-leaf stage)[2]
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Dosage:0.1 mg/L
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Administration:spray; single treatment
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Result:Increased dry mass of treated plants to 1.51 g, corresponding to a 111% dry mass increase relative to the untreated control (100% = 1.36 g).; Showed no statistically significant difference compared to untreated controls.
Chemical Information
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CAS No. 1704-28-5
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Molecular Weight 283.50
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Formula C18H37NO
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SMILES
O1C(C)CN(CCCCCCCCCCCC)CC1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Dodecyl-2,6-dimethylmorpholine Related Classifications
HY-W043791 Related Classifications
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