1429624-84-9
1429624-84-9
Chemical Structure
PI4KIIIbeta-IN-9
- CAS No.: 1429624-84-9
- Formula:C23H25N3O5S2
- Molecular Weight:487.59
IUPAC Name: N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)cyclopentanecarboxamide
InChIKey: KAXNDTMKFONXJM-UHFFFAOYSA-N
SMILES: CC(N=C1NC(C2CCCC2)=O)=C(S1)C3=CC=C(C(S(=O)(NC4=CC=C(O)C=C4)=O)=C3)OC
Biological Activity: PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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PI4KIIIbeta-IN-9 | 99.18% | PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.82
HY-100198PI4KIIIbeta-IN-10 -
Similarity Score 0.60
HY-172256PI4KIII beta inhibitor 5 -
Similarity Score 0.55
HY-172255PI4KIII beta inhibitor 4 -
Similarity Score 0.55
HY-161357KR-27370 -
Similarity Score 0.52
HY-12046PIK-93 -
Similarity Score 0.51
HY-157674HSD17B13-IN-46 -
Similarity Score 0.51
HY-136806PI3K-IN-12 -
Similarity Score 0.50
HY-12343ML277 -
Similarity Score 0.50
HY-112608CHMFL-PI3KD-317 -
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