150-25-4
Chemical Structure
Bicine
- CAS No.: 150-25-4
- Formula:C6H13NO4
- Molecular Weight:163.17
IUPAC Name: bis(2-hydroxyethyl)glycine
InChIKey: FSVCELGFZIQNCK-UHFFFAOYSA-N
SMILES: O=C(O)CN(CCO)CCO
Biological Activity: Bicine is a buffer used in physiological research. Bicine is a derivative of the simple amino acid glycine that increases the sensitivity of guanosine enzyme histochemical detection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bicine | 98.0% | Bicine is a buffer used in physiological research. Bicine is a derivative of the simple amino acid glycine that increases the sensitivity of guanosine enzyme histochemical detection. | ||||||||||||||||||||
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Tricine | 99.89% | Tricine is widely used as a buffer in protein electrophoresis, nucleic acid analysis, and immunology, which can help adjust pH and stabilize chemical reactions. In addition, the compound can also be used in research in certain medical fields, such as in antibody detection and drug screening. | ||||||||||||||||||||
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5-Hydroxypentanoic acid | 5-Hydroxypentanoic acid is a PROTAC linker. 5-Hydroxypentanoic acid can be used in the synthesis of PROTAC AR-V7 degrader-1 (HY-145479). | |||||||||||||||||||||
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7-Hydroxyheptanoic acid | 7-Hydroxyheptanoic acid is an intermediate. 7-Hydroxyheptanoic acid can be dehydrolyzed to Pimelic acid (HY-Y1139). Pimelic acid derivatives can participate in the biosynthesis of lysine. | |||||||||||||||||||||
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Sodium 5-hydroxypentanoate | 97.0% | Sodium 5-hydroxypentanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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6-Hydroxyhexanoic acid | 99.14% | 6-Hydroxyhexanoic acid (6-HHA) is a bacterial effector molecule with metabolic and immunomodulatory activities. 6-Hydroxyhexanoic acid activates the JAK1-STAT1 signaling pathway, promotes phenotypic conversion of M2 macrophages to M1 macrophages, and exerts anti-tumor effects by regulating macrophage polarization. 6-Hydroxyhexanoic acid inhibits lipolysis in adipocytes mediated by Gαi family GPCR, and reduces high-fat diet-induced weight gain and obesity. 6-Hydroxyhexanoic acid can be used in studies related to pancreatic ductal adenocarcinoma, obesity, and insulin resistance. | ||||||||||||||||||||
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Potassium 6-hydroxyhexanoate | Potassium 6-hydroxyhexanoate (6-Hydroxyhexanoic acid, potassium salt) is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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N-(2-Hydroxyethyl)iminodiacetic Acid | 97.0% | N-(2-Hydroxyethyl)iminodiacetic Acid is a Glycine (HY-Y0966) derivative. | ||||||||||||||||||||
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2-Aminooxyethyliminodiacetic acid hydrochloride | 2-Aminooxyethyliminodiacetic Acid Hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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8-Hydroxyoctanoic acid | ≥98.0% | 8-Hydroxyoctanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Propyldiethanolamine | Propyldiethanolamine is a biochemical reagent. | |||||||||||||||||||||
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References
- [1]. Taha M, et al. Mixed-ligand complex formation equilibria of cobalt (II), nickel (II), and copper (II) with N, N-bis (2-hydroxyethyl) glycine (bicine) and some amino acids[J]. Journal of Chemical & Engineering Data, 2005, 50(1): 157-163.
- [2]. ITO S, et al. Histochemical distribution of guanase in human tissues with guanine in bicine buffer as substrate[J]. Acta histochemica et cytochemica, 1986, 19(4): 437-449. [Content Brief]