1619237-95-4
Chemical Structure
Verlamelin B
- CAS No.: 1619237-95-4
- Formula:C44H69N7O11
- Molecular Weight:872.06
InChIKey: WLEVFTWABMMUQJ-JFIQTRDHSA-N
SMILES: O=C1[C@@]2([H])N(C([C@H](NC([C@H](NC(CCC[C@@H](OC([C@@H](NC([C@H](NC([C@@H](N1)CCC(N)=O)=O)CC3=CC=C(C=C3)O)=O)C(C)C)=O)CCCCCCCCC)=O)CO)=O)C)=O)CCC2
Biological Activity: Verlamelin B (Compound 147) is effective against plant pathogenic fungal and is a derivative of Verlamelin (HY-N14856).Verlamelin B exhibits potent plant protective activity in vivo, particularly against rice blast and barley powdery mildew. Verlamelin B causes morphological changes in fungal cells, such as swelling or expansion. Verlamelin B exhibits weaker antifungal activity in vitro against plant pathogens such as rice blast, Dipolaris zeae, and Botrytis cinerea. Verlamelin B is useful for research on antifungal activities against plant pathogens[1][2].
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Verlamelin B | Verlamelin B (Compound 147) is effective against plant pathogenic fungal and is a derivative of Verlamelin (HY-N14856).Verlamelin B exhibits potent plant protective activity in vivo, particularly against rice blast and barley powdery mildew. Verlamelin B causes morphological changes in fungal cells, such as swelling or expansion. Verlamelin B exhibits weaker antifungal activity in vitro against plant pathogens such as rice blast, Dipolaris zeae, and Botrytis cinerea. Verlamelin B is useful for research on antifungal activities against plant pathogens. | |||||||||||||||||||||
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- [1]. Ishidoh K, et al.. Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp. J Antibiot (Tokyo). 2014 Jun;67(6):459-63. [Content Brief]
- [2]. Zhang L, et al. Secondary metabolites from hypocrealean entomopathogenic fungi: novel bioactive compounds. Nat Prod Rep. 2020 Sep 23;37(9):1181-1206. [Content Brief]
Keywords
