166374-49-8
166374-49-8
Chemical Structure
Naxifylline
Synonym(s): BG9719; CVT-124
- CAS No.: 166374-49-8
- Formula:C18H24N4O3
- Molecular Weight:344.41
IUPAC Name: 1,3-dipropyl-8-((1S,2R,4S,5S,6S)-3-oxatricyclo[3.2.1.02,4]octan-6-yl)-1H-purine-2,6(3H,9H)-dione
InChIKey: OQCJPFYWFGUHIN-GJKBLCTNSA-N
SMILES: CCCN1C2=C(C(N(C1=O)CCC)=O)NC([C@@H]3[C@@]4([H])[C@@]5([H])[C@]([C@](C3)([H])C4)([H])O5)=N2
Biological Activity: Naxifylline (BG9719; CVT-124) is a potent and selective A1-adenosine antagonist with Ki values of 0.67 and 0.45 nM for rat and cloned human A1-receptors, respectively. Naxifylline is a potassium-sparing diuretic for the study of edema associated with congestive heart failure[1].
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Naxifylline | Naxifylline (BG9719; CVT-124) is a potent and selective A1-adenosine antagonist with Ki values of 0.67 and 0.45 nM for rat and cloned human A1-receptors, respectively. Naxifylline is a potassium-sparing diuretic for the study of edema associated with congestive heart failure. | |||||||||||||||||||||
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