173531-58-3
173531-58-3
Chemical Structure
Naphthoquine phosphate
- CAS No.: 173531-58-3
- Formula:C24H34ClN3O9P2
- Molecular Weight:605.94
IUPAC Name: 2-((tert-butylamino)methyl)-4-((7-chloroquinolin-4-yl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol bis(phosphate)
InChIKey: QTYPWHKJEDCDNH-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C(NC2=C(CCCC3)C3=C(O)C(CNC(C)(C)C)=C2)=CC=N4)C4=C1.O=P(O)(O)O.O=P(O)(O)O
Biological Activity: Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Naphthoquine phosphate | 99.33% | Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine. | ||||||||||||||||||||
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References
- [1]. Wang JY, et al. Naphthoquine phosphate and its combination with artemisinine. Acta Trop. 2004 Feb;89(3):375-81. [Content Brief]
- [2]. Wang JY, et al. Therapeutic efficacy of naphthoquine phosphate combined with artemisinine against Plasmodium knowlesi. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008 Dec 30;26(6):442-4. [Content Brief]
Keywords
