1. Anti-infection
  2. Parasite
  3. Naphthoquine phosphate

Naphthoquine phosphate 

Cat. No.: HY-17036 Purity: 99.71%
Handling Instructions

Naphthoquine phosphate is antimalarial drug.

For research use only. We do not sell to patients.

Naphthoquine phosphate Chemical Structure

Naphthoquine phosphate Chemical Structure

CAS No. : 173531-58-3

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Estimated Time of Arrival: December 31
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Estimated Time of Arrival: December 31
100 mg USD 180 In-stock
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500 mg USD 288 In-stock
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Description

Naphthoquine phosphate is antimalarial drug. IC50 Value: N/A Target: Antiparasitic Naphthoquine phosphate and artemisinine are two antimalarials developed in China. Both drugs have proven to be efficacious and well tolerated as monotherapy as well as in combination in patients suffering from malaria. The Co-naphthoquine, a novel antimalarial combination, is an oral fixed combination tablet of the naphthoquine phosphate and artemisinine. Artemisinin is characterised by a rapid onset of schizonticidal action and a short half-life. Parasite clearance is, however, often incomplete when it is employed as a single agent unless high dosages are used over several days, but such a regimen may reduce patient compliance and increase the danger of toxicity. Naphthoquine phosphate, by contrast, has a slower onset of action and a longer half-life, associated with a low recrudescence rate.

Molecular Weight

605.94

Formula

C₂₄H₃₄ClN₃O₉P₂

CAS No.

173531-58-3

SMILES

ClC1=CC=C(C(NC2=C(CCCC3)C3=C(O)C(CNC(C)(C)C)=C2)=CC=N4)C4=C1.O=P(O)(O)O.O=P(O)(O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 3.33 mg/mL (5.50 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6503 mL 8.2516 mL 16.5033 mL
5 mM 0.3301 mL 1.6503 mL 3.3007 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

NaphthoquineParasiteInhibitorinhibitorinhibit

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Product name:
Naphthoquine phosphate
Cat. No.:
HY-17036
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