1777832-90-2

TBAP-001 Chemical Structure
1777832-90-2

Chemical Structure

TBAP-001

  • CAS No.: 1777832-90-2
  • Formula:C27H23F2N7O3
  • Molecular Weight:531.51

IUPAC Name: 1-(3-(tert-butyl)-1-(3-fluorophenyl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea

InChIKey: AJFKKXIBHCRFJO-UHFFFAOYSA-N

SMILES: O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=CC(F)=C2)NC3=CC=C(OC4=C(N=C5)C(NC5=O)=NC=C4)C=C3F

Biological Activity: TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay[1].

Cat. No. Product Name Purity Description Pricing
HY-136567
TBAP-001 98.97% TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References