1777832-90-2
1777832-90-2
Chemical Structure
TBAP-001
- CAS No.: 1777832-90-2
- Formula:C27H23F2N7O3
- Molecular Weight:531.51
IUPAC Name: 1-(3-(tert-butyl)-1-(3-fluorophenyl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea
InChIKey: AJFKKXIBHCRFJO-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=CC(F)=C2)NC3=CC=C(OC4=C(N=C5)C(NC5=O)=NC=C4)C=C3F
Biological Activity: TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay[1].
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TBAP-001 | 98.97% | TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay. | ||||||||||||||||||||
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References
Keywords
