1787294-07-8
Chemical Structure
Remibrutinib
Synonym(s): LOU064
- CAS No.: 1787294-07-8
- Formula:C27H27F2N5O3
- Molecular Weight:507.53
IUPAC Name: N-(3-(6-amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide
InChIKey: CUABMPOJOBCXJI-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(F)=CC(C2=NC=NC(N)=C2OCCN(C)C(C=C)=O)=C1C)C3=CC=C(C4CC4)C=C3F
Biological Activity: Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood[1]. Remibrutinib has the potential for Chronic urticaria (CU) treatment[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Remibrutinib | 99.76% | Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment. | ||||||||||||||||||||
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Similarity Score 0.60
HY-130255BTK inhibitor 13 -
Similarity Score 0.52
HY-145884BTK-IN-8 -
Similarity Score 0.50
HY-176526BTK degrader-1 intermediate -
Similarity Score 0.47
HY-154946SUCNR1-IN-1 -
Similarity Score 0.45
HY-108691PF-06465469 -
Similarity Score 0.45
HY-Z1979Afatinib impurity 32 -
Similarity Score 0.44
HY-145835PERK-IN-5 -
Similarity Score 0.44
HY-145835A(S)-PERK-IN-5 -
Similarity Score 0.44
HY-135220PERK-IN-2 -
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