1807988-47-1
1807988-47-1
Chemical Structure
IITZ-01
- CAS No.: 1807988-47-1
- Formula:C26H23FN8O
- Molecular Weight:482.51
IUPAC Name: N2-(4-(1H-benzo[d]imidazol-2-yl)phenyl)-N4-(4-fluorophenyl)-6-morpholino-1,3,5-triazine-2,4-diamine
InChIKey: XGEDDGLPNSLBFE-UHFFFAOYSA-N
SMILES: FC1=CC=C(NC2=NC(N3CCOCC3)=NC(NC4=CC=C(C5=NC6=CC=CC=C6N5)C=C4)=N2)C=C1
Biological Activity: IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ.
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IITZ-01 | 98.18% | IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ. | ||||||||||||||||||||
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Keywords
