1873358-87-2

XY018 Chemical Structure
1873358-87-2

Chemical Structure

XY018

  • CAS No.: 1873358-87-2
  • Formula:C23H15F7N2O4
  • Molecular Weight:516.37

IUPAC Name: N-(2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-[1,1'-biphenyl]-4-yl)-2-(2-nitrophenyl)acetamide

InChIKey: MNVXADPCMINSEC-UHFFFAOYSA-N

SMILES: OC(C(F)(F)F)(C1=CC(F)=C(C(C=C2)=CC=C2NC(CC(C=CC=C3)=C3[N](=O)=O)=O)C=C1)C(F)(F)F

Biological Activity: XY018 is a potent ROR-γ-selective antagonist. XY018 inhibits ROR-γ constitutive activity in 293T cells with high potency (EC50, 190 nM). XY018 binds to the ROR-γ hydrophobic ligand binding domain (LBD)[1].

Cat. No. Product Name Purity Description Pricing
HY-120210 		XY018 99.68% XY018 is a potent ROR-γ-selective antagonist. XY018 inhibits ROR-γ constitutive activity in 293T cells with high potency (EC50, 190 nM). XY018 binds to the ROR-γ hydrophobic ligand binding domain (LBD).
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