1873358-87-2
1873358-87-2
Chemical Structure
XY018
- CAS No.: 1873358-87-2
- Formula:C23H15F7N2O4
- Molecular Weight:516.37
IUPAC Name: N-(2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-[1,1'-biphenyl]-4-yl)-2-(2-nitrophenyl)acetamide
InChIKey: MNVXADPCMINSEC-UHFFFAOYSA-N
SMILES: OC(C(F)(F)F)(C1=CC(F)=C(C(C=C2)=CC=C2NC(CC(C=CC=C3)=C3[N](=O)=O)=O)C=C1)C(F)(F)F
Biological Activity: XY018 is a potent ROR-γ-selective antagonist. XY018 inhibits ROR-γ constitutive activity in 293T cells with high potency (EC50, 190 nM). XY018 binds to the ROR-γ hydrophobic ligand binding domain (LBD)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XY018 | 99.68% | XY018 is a potent ROR-γ-selective antagonist. XY018 inhibits ROR-γ constitutive activity in 293T cells with high potency (EC50, 190 nM). XY018 binds to the ROR-γ hydrophobic ligand binding domain (LBD). | ||||||||||||||||||||
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