1887237-54-8

I-BET567 Chemical Structure
1887237-54-8

Chemical Structure

I-BET567

  • CAS No.: 1887237-54-8
  • Formula:C17H18ClN5O2
  • Molecular Weight:359.81

IUPAC Name: (2S,4R)-1-acetyl-4-((5-chloropyrimidin-2-yl)amino)-2-methyl-1,2,3,4-tetrahydroquinoline-6-carboxamide

InChIKey: KNBYFXZNSOENGW-LKFCYVNXSA-N

SMILES: O=C(C1=CC2=C(N(C(C)=O)[C@@H](C)C[C@H]2NC3=NC=C(Cl)C=N3)C=C1)N

Biological Activity: I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC50s of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammation[1].

Cat. No. Product Name Purity Description Pricing
HY-142520
I-BET567 99.49% I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC50s of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammation.
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