1887237-54-8
1887237-54-8
Chemical Structure
I-BET567
- CAS No.: 1887237-54-8
- Formula:C17H18ClN5O2
- Molecular Weight:359.81
IUPAC Name: (2S,4R)-1-acetyl-4-((5-chloropyrimidin-2-yl)amino)-2-methyl-1,2,3,4-tetrahydroquinoline-6-carboxamide
InChIKey: KNBYFXZNSOENGW-LKFCYVNXSA-N
SMILES: O=C(C1=CC2=C(N(C(C)=O)[C@@H](C)C[C@H]2NC3=NC=C(Cl)C=N3)C=C1)N
Biological Activity: I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC50s of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
I-BET567 | 99.49% | I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC50s of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
