199596-05-9
199596-05-9
Chemical Structure
JIB-04
- CAS 番号: 199596-05-9
- Formula:C17H13ClN4
- Molecular Weight:308.76
IUPAC Name: (E)-5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine
InChIKey: YHHFKWKMXWRVTJ-OQKWZONESA-N
SMILES: ClC1=CN=C(N/N=C(C2=CC=CC=C2)/C3=NC=CC=C3)C=C1
Biological Activity: JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50s of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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JIB-04 | 98.84% | JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50s of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-107842R(Z)-JIB-04 (Standard) -
Similarity Score 0.73
HY-169919HDM-IN-1 -
Similarity Score 0.61
HY-W075531N1,N3-Di(pyridin-2-yl)benzene-1,3-diamine -
Similarity Score 0.60
HY-15478WZ811 -
Similarity Score 0.60
HY-N19235Actionpolymorphol D -
Similarity Score 0.60
HY-18973Dp44mT -
Similarity Score 0.59
HY-126773Dp2mT -
Similarity Score 0.58
HY-156793hRIO2 kinase ligand-1 -
Similarity Score 0.58
HY-W834690G6Pase catalytic enzyme-IN-1 -
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