2010159-60-9
Chemical Structure
(S,R,S)-AHPC-PEG2-NH2
Synonym(s): VH032-PEG2-NH2 ; VHL Ligand-Linker Conjugates 3 ; E3 ligase Ligand-Linker Conjugates 6 Free Base
- CAS No.: 2010159-60-9
- Formula:C28H41N5O6S
- Molecular Weight:575.72
IUPAC Name: (2S,4R)-1-((S)-2-(2-(2-(2-aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: XWDVNBVOCHHWAD-OTNCWRBYSA-N
SMILES: O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Biological Activity: (S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
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(S,R,S)-AHPC-PEG2-NH2 | 98.06% | (S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG2-NH2 (Standard) | ≥98% | (S,R,S)-AHPC-PEG2-NH2 (Standard) is the analytical standard of (S,R,S)-AHPC-PEG2-NH2 (HY-103603A). This product is intended for research and analytical applications. (S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. | ||||||||||||||||||||
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Similarity Score 1.00
HY-103603C(S,S,S)-AHPC-PEG2-NH2 -
Similarity Score 0.99
HY-103603R(S,R,S)-AHPC-PEG2-NH2 hydrochloride (Standard) -
Similarity Score 0.98
HY-103603B(S,R,S)-AHPC-PEG2-NH2 dihydrochloride -
Similarity Score 0.95
HY-103602A(S,R,S)-AHPC-PEG3-NH2 -
Similarity Score 0.94
HY-103602(S,R,S)-AHPC-PEG3-NH2 hydrochloride -
Similarity Score 0.93
HY-103602B(S,R,S)-AHPC-PEG3-NH2 dihydrochloride -
Similarity Score 0.93
HY-136008(S,R,S)-AHPC-PEG1-NH2 -
Similarity Score 0.93
HY-136008A(S,R,S)-AHPC-PEG1-NH2 dihydrochloride -
Similarity Score 0.92
HY-176422(S,R,S)-AHPC-Amide-PEG2-C2-NH2 -
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