202475-60-3
202475-60-3
Chemical Structure
JANEX-1
Synonym(s): WHI-P131; Jak3 inhibitor I
- CAS No.: 202475-60-3
- Formula:C16H15N3O3
- Molecular Weight:297.31
IUPAC Name: 4-((6,7-dimethoxyquinazolin-4-yl)amino)phenol
InChIKey: HOZUXBLMYUPGPZ-UHFFFAOYSA-N
SMILES: OC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1
Biological Activity: JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JANEX-1 | 99.63% | JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2. | ||||||||||||||||||||
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