202475-60-3

JANEX-1 Chemical Structure
202475-60-3

Chemical Structure

JANEX-1

Synonym(s): WHI-P131; Jak3 inhibitor I

  • CAS No.: 202475-60-3
  • Formula:C16H15N3O3
  • Molecular Weight:297.31

IUPAC Name: 4-((6,7-dimethoxyquinazolin-4-yl)amino)phenol

InChIKey: HOZUXBLMYUPGPZ-UHFFFAOYSA-N

SMILES: OC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1

Biological Activity: JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2.

Cat. No. Product Name Purity Description Pricing
HY-15508 		JANEX-1 99.63% JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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