2281-22-3
Chemical Structure
S-Allylmercaptocysteine
- CAS No.: 2281-22-3
- Formula:C6H11NO2S2
- Molecular Weight:193.29
IUPAC Name: S-(allylthio)-L-cysteine
InChIKey: WYQZZUUUOXNSCS-YFKPBYRVSA-N
SMILES: C=CCSSC[C@H](N)C(O)=O
Biological Activity: S-allylmercaptocysteine, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation[1][2][3].
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S-Allylmercaptocysteine | 95.0% | S-allylmercaptocysteine, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation. | ||||||||||||||||||||
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References
- [1]. Tong D, et al. S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-β signaling pathway in cancer cells. Oncol Rep. 2014;32(3):1124-1132. [Content Brief]
- [2]. Zhu X, et al. S-Allylmercaptocysteine Attenuates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation. Nutrients. 2017;9(2):166. Published 2017 Feb 20. [Content Brief]
- [3]. Li C, et al. S-Allylmercaptocysteine attenuates Bleomycin-induced pulmonary fibrosis in mice via suppressing TGF-β1/Smad and oxidative stress pathways. Int Immunopharmacol. 2020;79:106110. [Content Brief]
