23256-33-9
23256-33-9
Chemical Structure
Dimaprit dihydrochloride
- CAS No.: 23256-33-9
- Formula:C6H17Cl2N3S
- Molecular Weight:234.19
IUPAC Name: 3-(dimethylamino)propyl carbamimidothioate dihydrochloride
InChIKey: DFWCPLGXFMSUCW-UHFFFAOYSA-N
SMILES: NC(SCCCN(C)C)=N.[H]Cl.[H]Cl
Biological Activity: Dimaprit dihydrochloride is a selective histamine H2 receptor agonist, it also inhibits nNOS with an IC50 of 49 μM. Dimaprit dihydrochloride can stimulate gastric acid secretion[1][2].
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Dimaprit dihydrochloride | 99.14% | Dimaprit dihydrochloride is a selective histamine H2 receptor agonist, it also inhibits nNOS with an IC50 of 49 μM. Dimaprit dihydrochloride can stimulate gastric acid secretion. | ||||||||||||||||||||
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References
- [1]. Parsons ME, et, al. Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) - a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology. Agents Actions. 1977 Mar; 7(1): 31-7. [Content Brief]
- [2]. Paquay JB, et, al. Nitric oxide synthase inhibition by dimaprit and dimaprit analogues. Br J Pharmacol. 1999 May; 127(2): 331-4. [Content Brief]
Keywords
