2369751-30-2
2369751-30-2
Chemical Structure
G150
- CAS No.: 2369751-30-2
- Formula:C18H16Cl2N4O2
- Molecular Weight:391.25
IUPAC Name: 1-(9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-hydroxyethan-1-one
InChIKey: VVUOUIPXYFIWLE-UHFFFAOYSA-N
SMILES: NC1=CC=C(C2=C3C(NC4=C3CN(C(CO)=O)CC4)=C(Cl)C(Cl)=C2)C=N1
Biological Activity: G150 is a highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with an IC50 of 10.2 nM. G150 represses dsDNA-triggered interferon expression, and G150 can be used for the research of inflammatory[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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G150 | 99.20% | G150 is a highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with an IC50 of 10.2 nM. G150 represses dsDNA-triggered interferon expression, and G150 can be used for the research of inflammatory. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-147129cGAS-IN-9 -
Similarity Score 0.75
HY-133916G140 -
Similarity Score 0.70
HY-187079cGAS-IN-5-CH2-COOH -
Similarity Score 0.60
HY-187080cGAS-IN-5-CH2-amido-C9-NH2 -
Similarity Score 0.51
HY-170362cGAS-IN-4 -
Similarity Score 0.51
HY-170362A(R)-cGAS-IN-4 -
Similarity Score 0.49
HY-164288TDI-6570 -
Similarity Score 0.48
HY-172208PROTAC cGAS degrader-1 -
Similarity Score 0.47
HY-160546cGAS-IN-2 -
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