2435657-10-4
2435657-10-4
Chemical Structure
PARP7-IN-16
- CAS. Nr.: 2435657-10-4
- Formula:C25H26FN4NaO4
- Molecular Weight:488.49
InChIKey: HBKQJEOJZXXHOE-UHFFFAOYSA-M
SMILES: O=C([N-]C1=O)C2=CC=CC=C2N1CC3=CC=C(C(C(N4CCN(C(C4)=O)C(CC)CC)=O)=C3)F.[Na+]
Biological Activity: PARP7-IN-16 (compound 36) is a potent, selective and orally active inhibitor of PARP-1/2/7, with IC50s of 0.94, 0.87 and 0.21 nM, respectively. PARP7-IN-16 can be used for the research of breast cancer and prostate cancer[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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PARP7-IN-16 | 95.0% | PARP7-IN-16 (compound 36) is a potent, selective and orally active inhibitor of PARP-1/2/7, with IC50s of 0.94, 0.87 and 0.21 nM, respectively. PARP7-IN-16 can be used for the research of breast cancer and prostate cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-156419APARP7-IN-16 free base -
Similarity Score 0.72
HY-145328PARP-1/2-IN-1 -
Similarity Score 0.59
HY-137450Senaparib -
Similarity Score 0.59
HY-137450ASenaparib hydrochloride -
Similarity Score 0.50
HY-179208N-Descyclopropanecarbaldehyde Olaparib suberic acid -
Similarity Score 0.49
HY-10162ROlaparib (Standard) -
Similarity Score 0.49
HY-102035PARP-2-IN-1 -
Similarity Score 0.49
HY-75706N-Descyclopropanecarbaldehyde Olaparib -
Similarity Score 0.49
HY-13536AZD-2461 -
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