2446880-46-0
2446880-46-0
Chemical Structure
ND-011992
- CAS No.: 2446880-46-0
- Formula:C21H14F3N3O
- Molecular Weight:381.35
InChIKey: CAIODVXPWNFDFE-UHFFFAOYSA-N
SMILES: FC(F)(F)C(C=C1)=CC=C1OC(C=C2)=CC=C2NC3=NC=NC4=CC=CC=C43
Biological Activity: ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ND-011992 | 98.03% | ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study. | ||||||||||||||||||||
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References
Keywords
