2469975-55-9
2469975-55-9
Chemical Structure
Nur77 modulator 1
- CAS No.: 2469975-55-9
- Formula:C28H25N5O2S
- Molecular Weight:495.60
IUPAC Name: (E)-5-((8-methoxy-2-methylquinolin-4-yl)amino)-N'-(4-(methylthio)benzylidene)-1H-indole-2-carbohydrazide
InChIKey: ZDSQJUKYFCIYLG-MUFRIFMGSA-N
SMILES: CC1=NC2=C(OC)C=CC=C2C(NC3=CC4=C(NC(C(N/N=C/C5=CC=C(SC)C=C5)=O)=C4)C=C3)=C1
Biological Activity: Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell apoptosis. Anti-hepatoma activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nur77 modulator 1 | 98.16% | Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell apoptosis. Anti-hepatoma activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.54
HY-147905CDK9-IN-18 -
Similarity Score 0.52
HY-24504MBA-m1 -
Similarity Score 0.51
HY-124107UTA1inh-A1 -
Similarity Score 0.51
HY-162352SDU-071 -
Similarity Score 0.50
HY-155134Eg5-IN-1 -
Similarity Score 0.49
HY-1159014-PQBH -
Similarity Score 0.49
HY-124588MC3343 -
Similarity Score 0.48
HY-13962SGI-1027 -
Similarity Score 0.47
HY-147919Antifungal agent 33 -
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