252017-04-2
252017-04-2
Chemical Structure
AZD7545
- CAS No.: 252017-04-2
- Formula:C19H18ClF3N2O5S
- Molecular Weight:478.87
IUPAC Name: (R)-4-((3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)sulfonyl)-N,N-dimethylbenzamide
InChIKey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
SMILES: O=C(N(C)C)C1=CC=C(S(=O)(C2=CC=C(NC([C@@](C)(O)C(F)(F)F)=O)C(Cl)=C2)=O)C=C1
Biological Activity: AZD7545 is a potent, competitive, selective PDHK2 (pyruvate dehydrogenase kinase 2) inhibitor with IC50s of 36.8 nM, 6.4 nM for PDHK1 and PDHK2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD7545 | 99.91% | AZD7545 is a potent, competitive, selective PDHK2 (pyruvate dehydrogenase kinase 2) inhibitor with IC50s of 36.8 nM, 6.4 nM for PDHK1 and PDHK2, respectively. | ||||||||||||||||||||
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References
Keywords
