2531748-80-6
Chemical Structure
CDK2/4/6-IN-2
- CAS No.: 2531748-80-6
- Formula:C25H30FN9
- Molecular Weight:475.56
IUPAC Name: methyl 3-amino-3-(4-isopropylphenyl)propanoate hydrochloride
InChIKey: UJXLNDHBAIXHQB-UHFFFAOYSA-N
SMILES: CC(N1CCN(C2=CN=C(NC3=NC=CC(C4=CC5=C(N=CN5C(C)C)C(F)=N4)=N3)C=C2)CC1)C
Biological Activity: CDK2/4/6-IN-2 is a selective CDK2/4/6 inhibitor with IC50 values <1 μM. CDK2/4/6-IN-2 inhibits cells proliferation and phosphorylation of retinoblastoma protein at Ser807/811 in breast cancer cells. CDK2/4/6-IN-2 can be used for the research of cancer, such as breast cancer[1].
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CDK2/4/6-IN-2 | 98.20% | CDK2/4/6-IN-2 is a selective CDK2/4/6 inhibitor with IC50 values <1 μM. CDK2/4/6-IN-2 inhibits cells proliferation and phosphorylation of retinoblastoma protein at Ser807/811 in breast cancer cells. CDK2/4/6-IN-2 can be used for the research of cancer, such as breast cancer. | ||||||||||||||||||||
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Keywords