2550398-89-3
Chemical Structure
Benpyrine
- CAS No.: 2550398-89-3
- Formula:C16H16N6O
- Molecular Weight:308.34
IUPAC Name: (S)-4-((9H-purin-6-yl)amino)-1-benzylpyrrolidin-2-one
InChIKey: HUWOMAVUXTXEKT-LBPRGKRZSA-N
SMILES: O=C(N(CC1=CC=CC=C1)C2)C[C@@H]2NC3=C4C(NC=N4)=NC=N3
Biological Activity: Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 µM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Benpyrine | 99.26% | Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 µM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords