2550398-89-3
2550398-89-3
Chemical Structure
Benpyrine
- CAS No.: 2550398-89-3
- Formula:C16H16N6O
- Molecular Weight:308.34
IUPAC Name: (S)-4-((9H-purin-6-yl)amino)-1-benzylpyrrolidin-2-one
InChIKey: HUWOMAVUXTXEKT-LBPRGKRZSA-N
SMILES: O=C(N(CC1=CC=CC=C1)C2)C[C@@H]2NC3=C4C(NC=N4)=NC=N3
Biological Activity: Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 µM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Benpyrine | 99.26% | Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 µM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 1.00
HY-133807A(Rac)-Benpyrine -
Similarity Score 1.00
HY-133807B(R)-Benpyrine -
Similarity Score 0.57
HY-112104Meta-topolin -
Similarity Score 0.55
HY-B0941A6-Benzylaminopurine, suitable for plant cell culture -
Similarity Score 0.53
HY-141519PI-55 -
Similarity Score 0.53
HY-112522HS79 -
Similarity Score 0.53
HY-112522AHS80 -
Similarity Score 0.53
HY-121250Fasnall -
Similarity Score 0.53
HY-N0160Kinetin -
Explore the MedChemAI to find more analogs
