2556836-50-9
2556836-50-9
Chemical Structure
DGY-06-116
- CAS No.: 2556836-50-9
- Formula:C32H33ClN8O2
- Molecular Weight:597.11
IUPAC Name: 4-((2-acrylamidophenyl)amino)-N-(2-chloro-6-methylphenyl)-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide
InChIKey: HLRQYOGLZWIOPA-UHFFFAOYSA-N
SMILES: O=C(NC1=C(Cl)C=CC=C1C)C(C=N2)=C(NC3=C(NC(C=C)=O)C=CC=C3)N=C2NC4=CC=C(N5CCN(C)CC5)C=C4
Biological Activity: DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. DGY-06-116 inhibits FGFR1 with an IC50 of 8340 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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DGY-06-116 | 98.62% | DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. DGY-06-116 inhibits FGFR1 with an IC50 of 8340 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.77
HY-208739SRC tyrosine kinase IN-1 -
Similarity Score 0.70
HY-136848SM1-71 -
Similarity Score 0.65
HY-138966SM1-71-R -
Similarity Score 0.60
HY-144448FAK-IN-2 -
Similarity Score 0.59
HY-181502EGFR-IN-197 -
Similarity Score 0.59
HY-151961RSH-7 -
Similarity Score 0.59
HY-149824EGFR T790M/L858R-IN-2 -
Similarity Score 0.59
HY-117398HCI-2184 -
Similarity Score 0.57
HY-149365SIKs-IN-1 -
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