2682003-36-5
2682003-36-5
Chemical Structure
BI-4142
- CAS No.: 2682003-36-5
- Formula:C28H27N9O2
- Molecular Weight:521.57
IUPAC Name: 1-(4-(8-((3-methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperazin-1-yl)prop-2-en-1-one
InChIKey: JKBYBPNRTMHEGS-UHFFFAOYSA-N
SMILES: O=C(N1CCN(CC1)C2=NC=C3N=CN=C(C3=N2)NC4=CC=C(C(C)=C4)OC5=CC(N=CN6C)=C6C=C5)C=C
Biological Activity: BI-4142 is a potent, highly selective and orally active HER2 inhibitor with an IC50 of 5 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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BI-4142 | 98.02% | BI-4142 is a potent, highly selective and orally active HER2 inhibitor with an IC50 of 5 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-148810Zongertinib -
Similarity Score 0.78
HY-150023BI-1622 -
Similarity Score 0.55
HY-163419HER2-IN-18 -
Similarity Score 0.53
HY-163420HER2-IN-16 -
Similarity Score 0.52
HY-177895IAM1363 -
Similarity Score 0.52
HY-163418HER2-IN-17 -
Similarity Score 0.52
HY-177009Tucatinib analog B -
Similarity Score 0.52
HY-163421hERG-IN-2 -
Similarity Score 0.52
HY-163417HER2-IN-15 -
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