HER2-IN-18
HER2-IN-18 is a HER2 inhibitor, with an IC50 less than 200 nM for HER-YVMA and HER-WT. HER2-IN-18 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3031413-03-0
- Formula: C26H24N8O2
- Molecular Weight:480.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
[1]|
HER2(WT) <200 nM (IC50) |
HER2 YVMA <200 nM (IC50) |
EGFR (WT) 500-1500 n nM (IC50) |
Chemical Information
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CAS No. 3031413-03-0
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Molecular Weight 480.52
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Formula C26H24N8O2
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SMILES
C=CC(N1CCC(C1)C2=C3C(NC4=CC(C)=C(C=C4)OC5=CC6=NC=NN6C=C5)=NC=NN3C=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HER2-IN-18 Related Classifications
HY-163419 Related Classifications
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