HER2-IN-17
HER2-IN-17 (Compound 2) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 <200 nM. HER2-IN-17 inhibits proliferation of HER2 YVMA mutated BaF3 cells with an IC50 <200 nM and amliorates non-small-cell lung cancer (NSCLC).
For research use only. We do not sell to patients.
- CAS No.: 3031412-84-4
- Formula: C28H24N10O2
- Molecular Weight:532.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Biological Activity
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Her2 exon 20 YVMA insertion <200 nM (IC50) |
Chemical Information
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CAS No. 3031412-84-4
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Molecular Weight 532.56
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Formula C28H24N10O2
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SMILES
C=CC(N1CC(C1)N2C=C(C=N2)C3=C4C(NC5=CC=C(C(C)=C5)OC6=CC7=NC=NN7C=C6)=NC=NN4C=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HER2-IN-17 Related Classifications
HY-163418 Related Classifications
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