2761424-76-2
2761424-76-2
Chemical Structure
mGluR5 antagonist-1
- CAS No.: 2761424-76-2
- Formula:C23H18N4O2
- Molecular Weight:382.41
InChIKey: OIYWWKBIBPZHKJ-UHFFFAOYSA-N
SMILES: CN1C2=NC=NC(C#CC3=CC=CC=C3)=C2C=C1C(NC4=CC=C(OC)C=C4)=O
Biological Activity: mGluR5 antagonist-1 is an orally active mGluR5 antagonist with an IC50 value of 11.5 nM. mGluR5 antagonist-1 has anti-depressant effect. mGluR5 antagonist-1 can be used for the study of depressive disorder[1].
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mGluR5 antagonist-1 | 98.80% | mGluR5 antagonist-1 is an orally active mGluR5 antagonist with an IC50 value of 11.5 nM. mGluR5 antagonist-1 has anti-depressant effect. mGluR5 antagonist-1 can be used for the study of depressive disorder. | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.52
HY-1480385-HT3 antagonist 5 -
Similarity Score 0.52
HY-112355Aurora kinase inhibitor-2 -
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HY-118232VUF8504 -
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HY-144804VEGFR-2-IN-17 -
Similarity Score 0.51
HY-155988Sirtuin modulator 6 -
Similarity Score 0.50
HY-144805VEGFR-2-IN-18 -
Similarity Score 0.50
HY-178740GI261520A -
Similarity Score 0.49
HY-144803VEGFR-2-IN-16 -
Similarity Score 0.49
HY-116452YLT192 -
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