2765796-41-4
Chemical Structure
Firefly luciferase-IN-1
- CAS No.: 2765796-41-4
- Formula:C19H16O3
- Molecular Weight:292.33
InChIKey: HEEMJVLKXPNKTL-XNTDXEJSSA-N
SMILES: O=C1C2=CC=C(C(O)=O)C=C2CC/C1=C\C3=CC=C(C=C3)C
Biological Activity: Firefly luciferase-IN-1 is a cell-permeable firefly luciferase inhibitor with an IC50 of 0.25 nM and a Ki of 1.72 nM. Firefly luciferase-IN-1 reversibly binds to the D-luciferin-occupied pocket of Fluc, competing with D-luciferin. Firefly luciferase-IN-1 effectively blocks Fluc/D-Luciferin (HY-12591A)-induced bioluminescence[1].
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Firefly luciferase-IN-1 | 99.57% | Firefly luciferase-IN-1 is a cell-permeable firefly luciferase inhibitor with an IC50 of 0.25 nM and a Ki of 1.72 nM. Firefly luciferase-IN-1 reversibly binds to the D-luciferin-occupied pocket of Fluc, competing with D-luciferin. Firefly luciferase-IN-1 effectively blocks Fluc/D-Luciferin (HY-12591A)-induced bioluminescence. | ||||||||||||||||||||
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