TE-11
Based on 1 Customer Validation
TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 μM. TE-11 ameliorates CD-like colitis, reduces MIF-induced eosinophil and neutrophil migration, and prevents M1 polarization and associated metabolic reprogramming.
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- Pureté : 99.68%
- CAS No.: 160488-11-9
- Formule: C16H13NO
- Masse moléculaire:235.28
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
TE-11 (20 µM) inhibits proinflammatory cytokine and RONS production in M1 activated macrophages without a direct antioxidative effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 160488-11-9
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Appearance Solid
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Masse moléculaire 235.28
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Formule C16H13NO
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Color White to light yellow
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SMILES
O=C1C2=CC=CC=C2CC/C1=C\C3=NC=CC=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 50 mg/mL (212.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2503 mL | 21.2513 mL | 42.5026 mL | 106.2564 mL |
| 5 mM | 0.8501 mL | 4.2503 mL | 8.5005 mL | 21.2513 mL | |
| 10 mM | 0.4250 mL | 2.1251 mL | 4.2503 mL | 10.6256 mL | |
| 15 mM | 0.2834 mL | 1.4168 mL | 2.8335 mL | 7.0838 mL | |
| 20 mM | 0.2125 mL | 1.0626 mL | 2.1251 mL | 5.3128 mL | |
| 25 mM | 0.1700 mL | 0.8501 mL | 1.7001 mL | 4.2503 mL | |
| 30 mM | 0.1417 mL | 0.7084 mL | 1.4168 mL | 3.5419 mL | |
| 40 mM | 0.1063 mL | 0.5313 mL | 1.0626 mL | 2.6564 mL | |
| 50 mM | 0.0850 mL | 0.4250 mL | 0.8501 mL | 2.1251 mL | |
| 60 mM | 0.0708 mL | 0.3542 mL | 0.7084 mL | 1.7709 mL | |
| 80 mM | 0.0531 mL | 0.2656 mL | 0.5313 mL | 1.3282 mL | |
| 100 mM | 0.0425 mL | 0.2125 mL | 0.4250 mL | 1.0626 mL |
TE-11 Related Classifications
HY-173624 Related Classifications
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