2797-51-5
2797-51-5
Chemical Structure
Quinoclamine
- CAS No.: 2797-51-5
- Formula:C10H6ClNO2
- Molecular Weight:207.62
IUPAC Name: 2-amino-3-chloronaphthalene-1,4-dione
InChIKey: OBLNWSCLAYSJJR-UHFFFAOYSA-N
SMILES: O=C(C(Cl)=C(C1=O)N)C2=C1C=CC=C2
Biological Activity: Quinoclamine, a naphthoquinone derivative, is a NF-κB inhibitor. Quinoclamine exhibits anti-cancer activity[1][2].
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Quinoclamine | 99.56% | Quinoclamine, a naphthoquinone derivative, is a NF-κB inhibitor. Quinoclamine exhibits anti-cancer activity. | ||||||||||||||||||||
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Quinoclamine (Standard) | ≥98% | Quinoclamine (Standard) is the analytical standard of Quinoclamine. This product is intended for research and analytical applications. Quinoclamine, a naphthoquinone derivative, is a NF-κB inhibitor. Quinoclamine exhibits anti-cancer activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.84
HY-1152432-Chloro-1,4-naphthoquinone -
Similarity Score 0.80
HY-134760Vitamin impurity 3 -
Similarity Score 0.78
HY-W1029316,7-Dichloroquinoline-5,8-dione -
Similarity Score 0.77
HY-N2493Lawsone -
Similarity Score 0.77
HY-B0332Menadione -
Similarity Score 0.75
HY-W0154901,4-Naphthoquinone -
Similarity Score 0.74
HY-N7116RLawsone methyl ether (Standard) -
Similarity Score 0.74
HY-N6611Chimaphilin -
Similarity Score 0.74
HY-W452285Isoplumbagin -
Explore the MedChemAI to find more analogs
References
- [1]. Kwon H ,et al. Induction of differentiation of U-937 cells by 2-chloro-3-amino-1,4-naphthoquinone. Res Commun Mol Pathol Pharmacol. 1997 Aug;97(2):215-27. [Content Brief]
- [2]. Cheng WY, et al. Comprehensive evaluation of a novel nuclear factor-kappaB inhibitor, quinoclamine, by transcriptomic analysis. Br J Pharmacol. 2009 Jul;157(5):746-56. [Content Brief]
