2839338-28-0
2839338-28-0
Chemical Structure
CDK8-IN-11
- CAS No.: 2839338-28-0
- Formula:C19H15F3N4O2
- Molecular Weight:388.34
IUPAC Name: (R)-5-(2-aminoethyl)pyrrolidin-2-one hydrochloride
InChIKey: MBIXOXMOHXFUFZ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(OC3=CC=C(N)N=C3)C=C2
Biological Activity: CDK8-IN-11 is a potent and selective CDK8 inhibitor with an IC50 value of 46 nM. CDK8-IN-11 inhibits WNT/β-catenin signaling pathway. CDK8-IN-11 can be used in the research of colon cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CDK8-IN-11 | 98.18% | CDK8-IN-11 is a potent and selective CDK8 inhibitor with an IC50 value of 46 nM. CDK8-IN-11 inhibits WNT/β-catenin signaling pathway. CDK8-IN-11 can be used in the research of colon cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.82
HY-18817AFG210 -
Similarity Score 0.69
HY-136658STAT3-IN-48 -
Similarity Score 0.68
HY-164551YLL545 -
Similarity Score 0.66
HY-136657SC-43 -
Similarity Score 0.65
HY-143491VS 8 -
Similarity Score 0.63
HY-10201Sorafenib -
Similarity Score 0.62
HY-160676sEH-IN-1 -
Similarity Score 0.62
HY-126920AFG206 -
Similarity Score 0.62
HY-I0669Regorafenib impurity 1 -
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