2839338-28-0
2839338-28-0
Chemical Structure
CDK8-IN-11
- CAS No.: 2839338-28-0
- Formula:C19H15F3N4O2
- Molecular Weight:388.34
IUPAC Name: 1-(4-((6-aminopyridin-3-yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
InChIKey: MBIXOXMOHXFUFZ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(OC3=CC=C(N)N=C3)C=C2
Biological Activity: CDK8-IN-11 is a potent and selective CDK8 inhibitor with an IC50 value of 46 nM. CDK8-IN-11 inhibits WNT/β-catenin signaling pathway. CDK8-IN-11 can be used in the research of colon cancer[1].
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CDK8-IN-11 | 98.18% | CDK8-IN-11 is a potent and selective CDK8 inhibitor with an IC50 value of 46 nM. CDK8-IN-11 inhibits WNT/β-catenin signaling pathway. CDK8-IN-11 can be used in the research of colon cancer. | ||||||||||||||||||||
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References
Keywords
