2863-34-5
2863-34-5
Chemical Structure
Bethanidine hydriodide
- CAS No.: 2863-34-5
- Formula:C10H16IN3
- Molecular Weight:305.16
InChIKey: IBRUMPJVDPHEFZ-UHFFFAOYSA-N
SMILES: CN/C(NC)=N/CC1=CC=CC=C1.I
Biological Activity: Bethanidine hydriodide is an orally active antihypertensive agent and adrenergic neuron blocker. Bethanidine hydriodide exerts its antihypertensive effect by inhibiting the release of norepinephrine from sympathetic nerve terminals. Bethanidine hydriodide exhibits anti-ventricular arrhythmic activity. Bethanidine hydriodide can be used in research related to hypertension, ventricular tachycardia, and ventricular fibrillation[1][2][3].
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Bethanidine hydriodide | Bethanidine hydriodide is an orally active antihypertensive agent and adrenergic neuron blocker. Bethanidine hydriodide exerts its antihypertensive effect by inhibiting the release of norepinephrine from sympathetic nerve terminals. Bethanidine hydriodide exhibits anti-ventricular arrhythmic activity. Bethanidine hydriodide can be used in research related to hypertension, ventricular tachycardia, and ventricular fibrillation. | |||||||||||||||||||||
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References
- [1]. BOURA AL, et al. Adrenergic neurone blockade and other acute effects caused by N-benzyl-N'N"-dimethylguanidine and its ortho-chloro derivative. Br J Pharmacol Chemother. 1963;20(1):36-55. [Content Brief]
- [2]. Bacaner MB, et al. Antiarrhythmic, antifibrillatory, and hemodynamic actions of bethanidine sulfate: an orally effective analog of bretylium for suppression of ventricular tachyarrhythmias. Am J Cardiol. 1982;50(4):728-734. [Content Brief]
- [3]. Gifford RW. Bethanidine sulfate—a new antihypertensive agent. JAMa. 1965 Sep 13;193(11):901-5.
