2976342-33-1
2976342-33-1
Chemical Structure
PARP-1-IN-3
- CAS No.: 2976342-33-1
- Formula:C21H17BrN2O3
- Molecular Weight:425.28
IUPAC Name: 4-bromo-N-(3-((2-carbamoylphenoxy)methyl)phenyl)benzamide
InChIKey: VYGPONYCLGMRIN-UHFFFAOYSA-N
SMILES: NC(C1=CC=CC=C1OCC2=CC=CC(NC(C3=CC=C(C=C3)Br)=O)=C2)=O
Biological Activity: PARP-1-IN-3, a benzamide derivative, is a potent PARP-1 inhibitor with IC50 values of 0.25 nM and 2.34 nM for PARP-1 and PARP-2, respectively. PARP-1-IN-3 induces apoptosis and arrest cell cycle at G2/M phase. PARP-1-IN-3 can be used in research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PARP-1-IN-3 | 99.80% | PARP-1-IN-3, a benzamide derivative, is a potent PARP-1 inhibitor with IC50 values of 0.25 nM and 2.34 nM for PARP-1 and PARP-2, respectively. PARP-1-IN-3 induces apoptosis and arrest cell cycle at G2/M phase. PARP-1-IN-3 can be used in research of cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.62
HY-160617SIRT2-IN-14 -
Similarity Score 0.62
HY-12345ML365 -
Similarity Score 0.60
HY-124838EG1 -
Similarity Score 0.60
HY-114307Ly93 -
Similarity Score 0.59
HY-169608BCR-ABL-IN-11 -
Similarity Score 0.59
HY-183887PD-L1-IN-11 -
Similarity Score 0.59
HY-114146CID 1375606 -
Similarity Score 0.58
HY-134258MEISi-1 -
Similarity Score 0.57
HY-139177PPARα agonist 2 -
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