30299-08-2
30299-08-2
Chemical Structure
Clinofibrate
Synonym(s): S-8527
- CAS No.: 30299-08-2
- Formula:C28H36O6
- Molecular Weight:468.58
IUPAC Name: 2,2'-((cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid)
InChIKey: BMOVQUBVGICXQN-UHFFFAOYSA-N
SMILES: CCC(OC1=CC=C(C2(C3=CC=C(OC(CC)(C)C(O)=O)C=C3)CCCCC2)C=C1)(C)C(O)=O
Biological Activity: Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Clinofibrate | 98.54% | Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor. | ||||||||||||||||||||
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Clinofibrate (Standard) | ≥98% | Clinofibrate (Standard) is the analytical standard of Clinofibrate. This product is intended for research and analytical applications. Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor. | ||||||||||||||||||||
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EPI-001 | 99.34% | EPI-001, a selective inhibitor of Androgen Receptor (AR), targets transactivation unit 5 (Tau-5) of the AR. EPI-001 can inhibit transactivation of the AR amino-terminal domain (NTD), with an IC50 of ~6 μM. EPI-001 is also a selective modulator of PPARγ. EPI-001 is active against castration-resistant prostate cancer. | ||||||||||||||||||||
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Ralaniten | 99.57% | Ralaniten (EPI-002) is a potent and orally active antagonist of the androgen receptor-N-terminal domain (AR-NTD). Ralaniten inhibits AR transcriptional activity, with IC50 of 7.4 μM. Ralaniten can be used for the research of castration-resistant prostate cancer (CRPC). | ||||||||||||||||||||
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LG190119 | J1075 is a selective Schistosoma mansoni HDAC8 modulator (with decreased affinity for human HDAC8). J1075 can induce apoptosis (Apoptosis) and death in schistosome cells. J1075 holds research value in the field of anti-parasitic agents. | |||||||||||||||||||||
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Nafenopin | 99.71% | Nafenopin (SU-13-437) is a peroxidase proliferator with liver tumor promoting activity. Nafenopin is also used as an anti-hyperlipoproteinemia compound. Nafenopin is able to induce oxidative stress in vivo, showing its effects on the liver. The mechanism of action of nafenopin has differentiated features compared to other non-genotoxic carcinogens. | ||||||||||||||||||||
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Choline fenofibrate (Standard) | ≥98% | Choline Fenofibrate (Standard) is the analytical standard of Choline Fenofibrate. This product is intended for research and analytical applications. Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid is a PPAR activator with antihyperlipidemic effect. | ||||||||||||||||||||
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Beclobrate | 98.01% | Beclobrate (Sgd 24774), a Fibric acid derivative, displays remarkable lipid lowering activity in rodents. | ||||||||||||||||||||
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Fenofibric acid | 99.94% | Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. | ||||||||||||||||||||
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Bisphenol A (3-chloro-2-hydroxypropyl)glycidyl ether | 95.30% | Bisphenol A (3-chloro-2-hydroxypropyl) glycidyl ether is a chlorinated derivative that is released during heat treatment of food cans, bulk storage containers, and food containers. Bisphenol A (3-chloro-2-hydroxypropyl) glycidyl ether is an endocrine disruptor that affects reproductive organs and brain development. | ||||||||||||||||||||
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Bisphenol A bis(3-chloro-2-hydroxypropyl) ether | Bisphenol A bis(3-chloro-2-hydroxypropyl) ether is an organic compound with potential antimicrobial activity. Bisphenol A bis(3-chloro-2-hydroxypropyl) ether can be widely used in coatings and plastics to improve the strength and durability of materials. Bisphenol A bis(3-chloro-2-hydroxypropyl) ether also plays an important role in textile processing, improving the wrinkle resistance and abrasion resistance of fabrics. | |||||||||||||||||||||
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(3R,4S)-Hexestrol dipropionate | (3R,4S)-Hexestrol dipropionate (hexestrol dipropionate) is a synthetic estrogen with uterine contraction-relieving activity. (3R,4S)-Hexestrol dipropionate can be used for the research of diseases such as recurrent preterm birth and spontaneous abortion. | |||||||||||||||||||||
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