313-67-7
313-67-7
Chemical Structure
Aristolochic acid A
Synonym(s): Aristolochic acid I; TR 1736
- CAS No.: 313-67-7
- Formula:C17H11NO7
- Molecular Weight:341.27
IUPAC Name: 8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
InChIKey: BBFQZRXNYIEMAW-UHFFFAOYSA-N
SMILES: OC(C1=CC2=C(OCO2)C3=C4C(C(OC)=CC=C4)=CC([N+]([O-])=O)=C31)=O
Biological Activity: Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Aristolochic acid A | 99.91% | Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid A (Standard) | ≥98% | Aristolochic acid A (Standard) is the analytical standard of Aristolochic acid A. This product is intended for research and analytical applications. Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid A sodium | 99.93% | Aristolochic acid A (Aristolochic acid I) sodium is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A sodium significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A sodium reduces BLCAP gene expression in human cell lines. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid B (Standard) | ≥98% | Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B (HY-N0511). This product is intended for research and analytical applications. Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid Va | 98.74% | Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid C | 99.77% | Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid D (Standard) | ≥98% | Aristolochic acid D (Standard) (Aristolochic acid-IVa (Standard)) is the analytical standard of Aristolochic acid D (HY-N1465). This product is intended for research and analytical applications. Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC50: 4.673 μM) and CDK2 (IC50: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ariskanin A | Ariskanin A is a platelet aggregation inhibitor that exists in Aristolochia kankauensis and Aristolochia manshuriensis. Ariskanin A inhibits rabbit platelet aggregation. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
7-Hydroxyaristolochic acid A | 99.65% | 7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolactam I (Standard) | ≥98% | Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid III | 85.0% | Aristolochic acid III is a natural product that can be isolated from the leaves of Aristolochia debilis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aristolochic acid Ia | Aristolochic acid Ia is an oxidative metabolite of aristolochic acid I, which can be used to study the detoxification pathway of aristolochic acid metabolism. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
